In this episode of "Interesting Times," Ross Douthat interviews Vice President JD Vance in Rome, the day after the papal inauguration. They discuss the intersection of Vance's Catholic faith and his political views, particularly regarding economics, pro-life issues, and family policy. The conversation explores the tensions between the Trump administration's policies and the Pope's stances, especially on immigration. Vance defends the administration's approach to border security and deportation, addressing concerns about due process and potential abuses. They also delve into trade policies, discussing the goals of reducing the trade deficit and revitalizing American manufacturing. Finally, they touch on the potential impact of AI on society and the role of moral leadership in navigating these changes, with Vance expressing concerns about its effects on human connection and dating behaviors.