165 - AMA #24 [sneak peek]: Deep dive into blood glucose: why it matters, metrics to track, CGM data

Glucose homeostasis assessment requires moving beyond traditional metrics like fasting glucose and HbA1c, which often fail to capture the nuances of metabolic health. HbA1c measurements are frequently misleading due to variations in red blood cell lifespan, such as those caused by anemia or thalassemia. Continuous glucose monitors (CGMs) offer a superior alternative by providing real-time data on glucose excursions, allowing for a more precise understanding of metabolic function. Optimal health involves minimizing three core metrics: average blood glucose levels, glucose variability—measured by standard deviation—and the frequency of glucose peaks. Viewing metabolic health as a continuum rather than a binary state of diabetic or non-diabetic allows for proactive management, even in individuals without a formal diagnosis, ultimately supporting better long-term health and longevity outcomes.