This episode explores the intricacies of mergers and acquisitions (M&A) in the gambling industry, using the Melco case study as a primary example. Against the backdrop of the complex family dynamics within the Ho family's Macau gambling empire, the discussion analyzes Lawrence Ho's strategic partnership choices, highlighting the importance of selecting partners with strong reputations who won't interfere with his operations. More significantly, the episode delves into the financial aspects of M&A, demonstrating how to perform back-of-the-envelope calculations to assess a company's ability to pay and leverage, as illustrated by the MGM's potential acquisition of Melco. For instance, the analysis involves comparing the buyer's and target's Price-to-Earnings (PE) multiples and debt-to-EBITDA ratios to determine the potential for earnings per share (EPS) accretion or dilution. The instructors emphasize the human element in M&A, noting that factors beyond financial metrics, such as cultural nuances and stakeholder relationships, significantly influence deal outcomes. Ultimately, the episode underscores the importance of a holistic approach to M&A, integrating both qualitative and quantitative analyses to make informed decisions, and the crucial role of understanding the motivations and perspectives of all stakeholders involved.