This episode explores the controversial topic of linoleic acid, an omega-6 fatty acid found in seed oils, and its impact on cardiometabolic health. Against the backdrop of recent claims that seed oils are harmful, causing inflammation and various diseases, the interview delves into a comprehensive review co-authored by Dr. Bill Harris, a leading lipid researcher. More significantly, the discussion challenges the prevailing narrative by presenting evidence from biomarker studies and randomized controlled trials, which show a correlation between higher linoleic acid levels and improved health outcomes, including reduced cardiovascular disease and mortality. For instance, a meta-analysis of 13 studies involving 310,000 people demonstrated that higher linoleic acid intake was associated with longer lifespans and lower risks of heart disease. However, the discussion also acknowledges concerns about healthy user bias and the complexities of isolating the effects of linoleic acid from other dietary factors. In contrast to the common belief that seed oils are inflammatory, the evidence presented suggests that this is not the case, and that the omega-6 to omega-3 ratio is a misleading metric. What this means for consumers is that the demonization of seed oils is likely unwarranted, and that a balanced diet, including adequate omega-3 intake, is key to optimal health.