This episode explores the evolving landscape of AI and its impact on various industries, examining both technological advancements and business implications. Against the backdrop of 23andMe's bankruptcy filing, the hosts discuss the challenges of generating recurring revenue in a market where initial customer acquisition may be a one-time event. More significantly, the conversation pivots to MicroStrategy's continued Bitcoin acquisition strategy, prompting a debate on its sustainability and resemblance to a pyramid scheme. The discussion then shifts to the burgeoning M&A activity in the tech sector, with a record number of billion-dollar deals in Q1 2025, highlighting a potential shift in market sentiment and liquidity. For instance, the analysis of CB Insights data reveals a significant increase in unicorn exits compared to the previous year. The hosts then interview founders from three companies: Etched, focusing on their development of transformer-specific ASICs and their bet on the future dominance of transformer-based AI models; Skyflow, detailing their transition from a cybersecurity firm to an AI data security provider, emphasizing the growing importance of data privacy and security in the age of AI; and MedServe, showcasing their innovative medication cabinets designed to enhance security and compliance in smaller healthcare facilities. Emerging industry patterns reflected in these interviews include the increasing importance of specialized hardware for AI, the growing demand for AI-related security solutions, and the potential for significant disruption in niche markets with legacy technology. What this means for the future is a continued focus on specialized solutions, the need for robust data security measures, and the potential for significant growth in companies addressing unmet needs in established industries.