This AMA episode focuses on a framework for evaluating supplements, addressing the variability in individual needs. The podcast outlines six key questions to ask before taking any supplement, including assessing for deficiency vs. supraphysiological levels, lifespan/healthspan impact, biomarkers, mechanism of action, and risk/reward. Specific supplements like creatine, fish oil, and vitamin D are examined using this framework, highlighting the importance of understanding the mechanism of action and available data. Listeners gain a structured approach to evaluating supplement claims, enabling informed decision-making based on evidence and individual circumstances. The episode emphasizes the lack of regulation in the supplement industry, urging caution and thorough research.
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