This NPR Up First news podcast covers three main topics: the ongoing Russia-Ukraine conflict, the Trump administration's rollback of environmental regulations, and President Trump's proposed nuclear talks with Iran. The podcast features interviews with NPR correspondents who provide updates on each situation, including Russia's response to a proposed ceasefire, the potential environmental consequences of deregulation, and Iran's rejection of Trump's offer for nuclear talks. Specifically, the segment on the Russia-Ukraine conflict highlights Putin's recent visit to Kursk and his hawkish statements, suggesting a low likelihood of a ceasefire agreement. Listeners gain an understanding of current geopolitical events and their potential implications.