This NPR Up First news podcast covers three major stories. First, it reports on the near-complete defunding of USAID's foreign aid programs, resulting in the halting of numerous humanitarian projects and sparking criticism. Second, it details allegations of mistreatment and denial of legal counsel against two Venezuelan men detained at Guantanamo Bay. Finally, it discusses ongoing legal challenges against the Trump administration's dismissal of thousands of federal probationary employees. The podcast highlights the significant impact of these actions on global health initiatives, human rights, and the federal workforce. For example, the USAID cuts have led to the closure of over 1,000 kitchens in Sudan, exacerbating hunger issues.