This podcast episode discusses the intersection of artificial intelligence (AI) and cryptocurrency, featuring a conversation between the hosts and Tom Shaughnessy, an investor from Delphi Digital. The discussion traces the evolution of AI-crypto investments, highlighting early-stage infrastructure investments and the recent surge in AI agents. Shaughnessy emphasizes the importance of open-source AI models and the potential for decentralized development to compete with centralized AI labs, contrasting the "fat tail" of frontier models with the "long tail" of niche applications. A key takeaway is Shaughnessy's investment framework, prioritizing proprietary models, data, or business integrations, along with framework tooling and inference-time compute. The episode concludes with a discussion of the hosts' personal AI toolkits.