This podcast episode interviews Dr. Nathan Bryan, a nitric oxide expert, about the molecule's crucial role in health and longevity. The discussion covers nitric oxide's functions (vasodilation, stem cell release, telomere extension), the impact of diet and oral microbiome on its production (mouthwash negatively affects it), and its connection to conditions like diabetes and Alzheimer's. Dr. Bryan emphasizes the importance of avoiding mouthwash and fluoridated water to maintain a healthy oral microbiome for optimal nitric oxide levels. Listeners gain actionable insights into improving nitric oxide production through lifestyle changes and learn about Dr. Bryan's new book, "The Secret of Nitric Oxide."