Most people wait for inspiration. But what if you could train your brain to create on demand?

Rick Rubin has spent decades shaping the sound of legendary artists—Jay-Z, Johnny Cash, Metallica, and countless others—by tapping into the unseen forces of creativity. But what’s the secret behind his genius?

In this must-listen episode, Rick sits down with Dave to explore the science and soul of creativity, revealing how meditation, mindfulness, biohacking, and unconventional thinking fuel artistic breakthroughs. From rewiring your brain with meditation to stacking biohacks for peak creative flow, Rick shares the techniques that have kept him at the top of the music industry for over 40 years.

Dave and Rick go deep on the mental and physiological hacks that enhance creative performance, the surprising link between biohacking and artistry, and the rituals that keep Rick sharp, focused, and endlessly inspired.

What You’ll Learn:

• How Rick Rubin taps into creative flow—and how you can too

• The surprising connection between meditation and peak artistic performance

• Why biohacking isn’t just for longevity—it’s for creative mastery

• Rick’s favorite tools for mental clarity, focus, and creative breakthroughs

• The real secret behind working with the world’s biggest artists

• How to cultivate an environment that fuels creativity

Resources:

• 2025 Biohacking Conference: https://biohackingconference.com/2025

• Rick’s New Book The Creative Act: A way of Being: https://a.co/d/2bLbjeS

• Rick’s Instagram: https://www.instagram.com/rickrubin/?hl=en

• Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/

• Danger Coffee: https://dangercoffee.com

• Dave Asprey’s Website: https://daveasprey.com

• Dave Asprey’s Linktree: https://linktr.ee/daveasprey

• Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com

• Own an Upgrade Labs: https://ownanupgradelabs.com

• Upgrade Labs: https://upgradelabs.com

• 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com

SPONSORS:

Omni-Biotic | Visit omnibioticlife.com/dave and use code DAVE20 for 20% off.

BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 for 20% off your first order of PerfectAmino.

Timestamps:

• 00:00 – Trailer

• 00:51 – Intro to Rick Rubin

• 02:51 – Rick’s Musical Journey

• 03:06 – The Creative Process

• 08:31 – Biohacking & Sensitivity

• 13:46 – Meditation & Creativity

• 19:37 – Rick’s Weight Loss Story

• 29:21 – Eating Habits & Rhythm

• 29:55 – Advanced Biohacking

• 31:23 – Oxygen Therapy & Carbogen

• 35:16 – Peptides & Longevity

• 45:59 – Prayer, Gratitude & Performance

• 51:03 – Reflections on Life & Mortality

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Rick Rubin: How to Hack Your Mind for Creative Breakthroughs : 1251

The Human Upgrade: Biohacking for Longevity & Performance