This podcast episode focuses on three Amazon PPC optimization strategies. The speaker introduces and explains each optimization: tracking full business SKU economics for better budget and ACoS control; analyzing non-converting ad spend to identify and eliminate unprofitable keywords; and leveraging organic search data to identify keywords and products already performing well organically, but not yet included in paid campaigns. The speaker emphasizes the importance of measuring the interplay between organic and paid search results and provides practical examples, such as using a threshold of 25 clicks with zero orders to identify keywords for negative targeting. Listeners gain actionable advice to improve their Amazon PPC campaigns and increase profitability.