This Fresh Air Weekend interview podcast features Jesse Eisenberg, who discusses his film "A Real Pain," which he wrote, directed, and stars in alongside Kieran Culkin. The conversation explores the film's themes of suffering and the complexities of comparing personal struggles with historical trauma, using the backdrop of a Jewish heritage tour in Poland that includes visits to a death camp. Eisenberg reflects on his own experiences with mental health issues (OCD, depression, anxiety) and how they relate to his character's journey. The interview also includes a clip from the film showcasing the contrasting personalities of Eisenberg and Culkin's characters. A second interview with Pamela Anderson, discussing her new film "The Last Showgirl" and her career trajectory, follows the Eisenberg segment.