This interview podcast features Andrew Huberman, a neurobiology and ophthalmology professor, interviewing cosmologist Brian Keating about the origins of the universe. The conversation begins with a discussion of humanity's innate connection to astronomy, stemming from our ability to perceive the night sky and track time based on celestial movements. They delve into the history of astronomy, highlighting key figures like Galileo and Copernicus, and the development of the telescope and its impact on scientific discovery. The discussion also touches upon the scientific method, confirmation bias, and the emotional aspects of scientific pursuits, illustrated by Keating's personal experience with a retracted discovery. Listeners gain insights into the history of astronomy, the scientific process, and the human element within scientific endeavors, including the surprising connection between the development of eyeglasses and the invention of the telescope.