TWiV reviews RFK Jr’s demand to revoke polio vaccine, Wuhan lab samples do not include close relatives to SARS-CoV-2, using artificial intelligence to discover the RNA virosphere, and biomarkers that discriminate early and late phases of respiratory virus infections from a SARS-CoV-2 human challenge study.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Kathy Spindler, and Angela Mingarelli

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RFK Jr lawyer wants revocation of polio vaccine (CNN)
Wuhan lab has no samples close to SARS-CoV-2 (Nature)
Using AI to discover RNA virosphere (Cell)
SARS-CoV-2 human challenge reveals biomarkers (Nat Comm)
Does this challenge study pass the smell test? (TWiV 863)
Letters read on TWiV 1179
Timestamps by Jolene. Thanks!

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Angela – Science’s 2024 breakthrough of the year, Lenacapavir “the long shot”. NEJM papers with Lenacapavir trials: one and two.
Kathy – Bach Toccatta and Fugue on floor piano
Rich – Never Cry Wolf
Vincent – Common Raven and American Crow

Listener Pick

Jaan – Meute (one, two, three)

Intro music is by Ronald Jenkees

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TWiV 1179: Dark matter and warning signs

This Week in Virology