In the final episode of "No Stupid Questions," the hosts tackle the challenge of life's unanswered questions. They categorize these questions into educational, experiential, and existential types, stressing the need to build a tolerance for uncertainty. The conversation also highlights how to shift anxiety into excitement. Drawing on Viktor Frankl’s philosophy, they underscore the value of seeking meaning through serving others and engaging in purposeful work, rather than merely chasing comfort or happiness. The episode wraps up with thoughts on the importance of keeping the questions coming and discovering meaning in our everyday lives, even in the face of uncertainty.