The long-held dominant narrative about evolution is that it works like a tree. But as science has advanced in the last century, the idea of a family tree might not tell the full story anymore.

Evolutionary biologist David P. Mindell is a visiting scholar at UC Berkeley’s Museum of Vertebrate Zoology and the author of The Network of Life: A New View of Evolution which explores the concept of horizontal evolution alongside traditional Darwinian vertical evolution.

Greg and David discuss the importance of creating an updated narrative for evolutionary biology, the intricate nature of hybridization and horizontal gene transfer, the ethical implications of gene editing, and horizontal evolution’s potential application in medicine, agriculture, and public health.

*unSILOed Podcast is produced by University FM.*

Show Links:

Recommended Resources:

Guest Profile:

Professional Website
Museum of Vertebrate Zoology Website

His Work:

The Network of Life: A New View of Evolution

Episode Quotes:

Why horizontal evolution matters for understanding life

35:07: We really have to rethink what are the major mechanisms of evolution for all of life, not just what we see in animals or animals and plants. And this is why I think there's been some resistance to this idea that horizontal evolution really is highly consequential. It's just that we tend still to be human-centric, then animal-centric, and then maybe animal- and plant-centric. But if we really want to understand the evolution of all of life, then we can see that horizontal evolution is a big deal. There's both still vertical and horizontal, but we can't neglect the horizontal evolution from the basic, the most basic narrative, especially for the public, if we want them to understand how evolution operates.

How important is an overarching narrative in making sense of new discoveries?

07:37: Narrative is so important because, especially for the public, we understand stories. We're kind of wired to understand a story. And when you get the outlines of a story, you get a lot more information than just the basics of the story. You get new information, and you can plug it into the story as well. So having a narrative that is squared with our best science is valuable because it informs our understanding of evolutionary biology overall.

The power of decentralized evolution in rapid change

14:08: I talk in the book [The Network of Life] about inheritance when you're talking about how horizontal evolution can be decentralized. This is a powerful concept because they are supposed to have pros and cons of decentralization, but one of the advantages of it is its rapid change and rapid innovation. And this certainly can be advantageous for organisms, particularly when they're in a changeable environment, to suddenly get a new set of genes that have already been honed for millions of years in some other organism. If you can manage, if an organism can, if those can be expressed, and they are potentially useful, that's a way to get much faster adaptation than single base pair substitutions, which is what you usually see between parents and progeny.

Can we use horizontal evolution to our benefit—wisely?

41:50: Humans will be doing more and more forms of hybridizations or tinkering with life forms. If we can find some that carry particular functions that humans are interested in and talk briefly about bacteria that have the ability to remediate environmental toxins, this is something most everybody agrees could be a good thing, or bacteria that are capable of producing energy, and so we will eventually be using horizontal evolution to our benefit. You know, the question is, can we do it wisely enough?

471. Why It’s Time For Evolutionary Science to Evolve with David P. Mindell

unSILOed with Greg LaBlanc