This podcast explores the future of prompt engineering and the vital role of domain experts in developing effective AI applications. The speakers challenge the idea that there is a single "best" prompt or model, stressing the importance of iterative development and clearly defining problems. They advocate for leveraging domain expertise to create meaningful AI solutions. The discussion highlights the need for structured prompt engineering workflows, clear evaluation metrics, and well-crafted prompts, even as AI models become more advanced. Additionally, they address the limitations of current large language models and the ongoing necessity for human oversight and refinement.