In a Fresh Air interview, Annie Lowrey shares her experiences related to her Atlantic article on itch. Living with a rare liver disease, she endures a chronic and debilitating itch that can be so intense it feels hallucinatory. The discussion delves into the science behind itch, emphasizing that it is a separate sensation from pain, involving different neural pathways and recently identified non-histamine causes. While new research and medications targeting these pathways bring hope for improved treatments, the conversation also highlights a troubling lack of attention and research on itch compared to pain, revealing a significant gap in medical understanding and support for those who suffer.