In this podcast episode, a preventive neurologist explores 14 modifiable risk factors for dementia highlighted in the Lancet Commission report. While it's unlikely to completely reverse neurodegenerative diseases in their later stages, the neurologist stresses that early intervention and management of these factors—such as high LDL cholesterol, high blood pressure, diabetes, hearing and vision loss, head injuries, social isolation, depression, obesity, physical inactivity, alcohol use, smoking, air pollution, and environmental toxins—can significantly slow disease progression and enhance quality of life. The discussion also underscores the importance of personalized approaches, advocating for tailored strategies based on individual risk profiles and biomarkers. Additionally, the neurologist calls for more research into how menopause and hormone replacement therapy may influence dementia risk.
