Solving Stills Disease

Adult Stills disease, a systemic inflammatory disorder primarily affecting young adults, is characterized by quotidian fevers, evanescent rashes, and polyarthritis. The condition mirrors systemic onset juvenile arthritis, with both sharing similar manifestations, though sore throats are more common in adults. Named after George F. Still, who first described it in children, the disease's history extends back to the late 1800s, with significant contributions from Bywaters in 1971, who described it in adult females. Diagnosis is challenging due to the absence of specific tests, relying on clinical criteria and exclusion of other conditions. Management strategies range from high-dose steroids to biologic agents like IL-1 and IL-6 inhibitors, with treatment decisions guided by whether the disease presents systemically or primarily as articular.