In this engaging podcast episode, Sam Harris sits down with astrobiologist Sara Walker to discuss her intriguing book, "Life as No One Knows It." They explore how life emerges from physics and delve into the complexities of defining life, whether natural or artificial. The conversation addresses key questions about what life truly is, the importance of information in evolution, and the mysteries of the Fermi paradox. Walker also suggests innovative experiments to investigate the possibility of extraterrestrial life. With her fresh perspectives on assembly theory and a challenge to conventional notions of life, this episode invites listeners to expand their understanding of what life might mean in an expansive universe.