In this episode of The Curbsiders, Drs. Matthew Watto and Paul Nelson-Williams, along with guest host Dr. Moni Amin, interview Dr. Nathan Erdmann about inpatient COVID-19 management. Dr. Erdmann discusses the importance of clinical context over trending labs and the two main approaches to managing COVID-19: antiviral treatment and immunomodulation. The conversation covers admission criteria, outpatient therapeutics (including monoclonal antibodies and oral antivirals), and the use of remdesivir. They delve into the nuances of using inflammatory markers, the role of steroids, and the potential for additional immunomodulators like JAK inhibitors. The discussion also addresses anticoagulation strategies, the low rate of secondary bacterial infections, and considerations for vaccination post-COVID-19 infection. Dr. Erdmann emphasizes the importance of tailoring treatment to individual patients, especially those who are immunocompromised, and provides key take-home points for internists managing COVID-19 cases.
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