In this episode of The Curbsiders, Dr. Arielle Langer joins the hosts to discuss antiphospholipid antibody syndrome (APS). The podcast covers key aspects of APS, including its definition, clinical manifestations, diagnostic criteria, and management strategies. Dr. Langer explains the nuances of testing for APS, emphasizing the importance of clinical context and the limitations of available assays. She also reviews the Sapporo criteria for diagnosis and discusses the management of APS in both thrombotic and obstetric settings, including the use of anticoagulation and aspirin. The episode provides practical guidance for primary care physicians and other healthcare professionals on when to suspect APS, how to interpret lab results, and when to refer patients to a hematologist.
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