In this podcast episode, Dr. Attia and Tom explore the deep and often hidden impact of modern life on mental health, particularly the alarming increase in despair reflected in rising suicide and overdose rates. They discuss how sedentary lifestyles create disconnection and how our ancient instincts clash with today's realities. Despite medical advancements, they argue that a genuine sense of purpose and connection remains vital for overcoming contemporary challenges. The conversation emphasizes self-care, community, and mindful habits as essential to tackling the root causes of modern health issues, while also addressing the complex effects and risks associated with substance use.