Executive Editor Michael Roy speaks with Roscoe O. Brady, Jr., M.D., Ph.D., and Mark A. Halko, Ph.D., about their research on identifying and treating a network of connectivity in the brain corresponding to negative symptom severity in schizophrenia.

The difference between positive and negative symptoms in psychosis, and why the symptoms are important [2:39]
Identifying the treating the underlying circuitry of negative symptoms in the brain [6:25]
Discussion of the results of the study [10:20]
Symptom severity and the link between the prefrontal cortex and cerebellum [12:27]
Aspects of the study that are relevant for researchers, clinicians, and other mental health professionals [20:40]
What's next in this line of research and clinical care [25:40]

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July 2019: Treating Negative Symptoms in Schizophrenia

American Journal of Psychiatry Audio