This episode of AJP Audio features two articles from the February issue of AJP. First up, we have Nathaniel G. Harnett, Ph.D. (Harvard Medical School), discussing the impact of adversity and stress on racial disparities in childhood brain development among Black and White American children. Following that, Ziv Ben-Zion, Ph.D. (Yale University), discusses a non-exact replication study of a study published in AJP by Stevens et al. (previously featured on AJP Audio) looking at brain-based biotypes to guide treatment following trauma. And of course, we’ll check in with AJP Editor-in-Chief Dr. Ned Kalin about the rest of the February issue and how it all fits together.

Harnett interview [01:05]
How do less tangible factors like trauma, stress, and exposure to violence impact brain development? [03:07]
What do you mean by toxic stress? [04:41]
Why did you choose to focus on those regions of the brain? [06:01]
Regional variability and privacy concerns [07:50]
Limitations [09:11]
Future research [10:59]
Children and the limited control of their environment [12:10]
Ben-Zion interview [13:39]
Challenges of running a non-exact replication study [15:12]
Limitations [18:35]
Should researchers consider replication in study design? [21:26]
Future research [24:24]
Kalin interview [27:46]
Dumornay et al. [28:08]
Baldwin et al. [30:02]
Cleary et al. [31:38]
Ben-Zion et al. [34:15]
Hien et al. [37:08]

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February 2023: Adversity, Toxic Stress, and Racial Disparities in Children, and Evaluating the Evidence for Brain-Based Biotypes

American Journal of Psychiatry Audio