July 2024: Association of Occupational Dysfunction and Hospital Admissions With Different Polygenic Profiles in Bipolar Disorder

This podcast episode presents a comprehensive discussion on the genetic profiles associated with bipolar disorder and their implications for clinical practice. Dr. Lina Jonsson's research highlights strong links between polygenic scores and both occupational dysfunction and hospitalizations in bipolar disorder patients, with a need for targeted interventions to mitigate occupational challenges. Dr. Ned Kalin underlines the evolving landscape of psychiatric treatment through genetic insights, including the complexities of treatment-resistant depression, the impact of stress on depression, and long-term mental health implications on cardiometabolic health. The insights provided challenge current methodologies and call for a nuanced understanding of the multifaceted nature of mental health disorders.