This podcast episode addresses the alarming decline in metabolic health in the United States, primarily due to insulin resistance. The speakers emphasize the importance of monitoring fasting insulin levels and other metabolic markers to assess metabolic health, particularly for women in perimenopause and menopause. They also discuss the role of hormone replacement therapy (HRT), the importance of sleep, the benefits of protein in the first meal of the day, and the considerations for intermittent fasting. Additionally, the speakers highlight the impact of stress and trauma on health, emphasizing the need for stress management strategies and addressing unprocessed trauma to support overall well-being and weight loss.