This podcast episode features Andrew Huberman discussing the Huberman Lab's new philanthropic initiatives, aimed at supporting transformative research in mental health and performance, alongside addressing listener queries on health-related topics, from skin aging strategies to optimizing cold therapy. Notable discussions center on the importance of REM sleep for learning, the role of lifestyle factors over supplements like Shilajit for cognitive health, and practical tools for enhancing motivation, ultimately underscoring how science can enhance human well-being and engagement in life.