This podcast episode explores the power of AI in biology, particularly in understanding DNA. AI serves as a "Rosetta Stone" that can translate the complex language of biology, allowing researchers to predict protein folding and design molecular tools for fighting diseases. However, these advancements also come with risks, such as the potential misuse of AI-enabled biological threats. Striking a balance between leveraging AI's capabilities and implementing safeguards is crucial. The sections discuss the duality of DNA synthesis, security issues in ordering DNA encoding viruses, the use of AI tools in vaccine design, the intersection of open-source AI models and potential risks, the importance of responsible technology development, and the barriers preventing effective biosecurity measures. The tension between openness and security in science and technology is also highlighted, with the need for a policy framework to prevent the release of harmful systems. Overall, this episode emphasizes the importance of proactive measures and responsible actions in managing the risks associated with AI in biology.