This podcast episode explores the importance of negative keyword management in Amazon PPC campaigns. Low ACOS accounts, which have a low Advertising Cost of Sales, were found to have a high number of negative keywords and negative targets. The use of negative keyword management helps optimize PPC campaigns and improve advertising efficiency, leading to better ACOS performance. Strategies such as utilizing an upper limit search term ceiling, using lifetime search term history, conducting n-gram analysis, and performing novel negative keyword research are recommended for finding effective negative keywords. Regularly adding more negatives and monitoring their impact on ACOS is also emphasized.