This podcast episode focuses on diagnosing and managing depression, providing a structured overview for healthcare professionals. The discussion covers key assessment steps, including suicide risk evaluation and identifying high-risk groups, followed by diagnostic criteria and differential diagnoses. Management strategies, including medication choices (SSRIs, SNRIs, augmentation agents), psychotherapy, and return-to-work plans, are detailed. Specific examples include the use of the PHQ-2 and PHQ-9 scales for assessment and the "DIGFAST" mnemonic for identifying manic episodes. The episode aims to equip listeners with practical tools and knowledge for improved patient care in depression.