This podcast episode chronicles the journey of renowned neuroscientist Richie Davidson as he delves into exploring the mind, beginning with dreams, psychedelic experiences, and counterculture movements of the 1960s. It encompasses Davidson's pursuit of psychology and meditation, his transformative experiences during meditation retreats, and subsequent exploration of combining introspection and scientific observation to understand the mind. Davidson's engagement with the Dalai Lama and his encounter with skeptical retreatants highlight the complexities of understanding the mind. Ultimately, he realized the grandeur of his attempt – translating Eastern and Western perspectives – was doomed to fail, revealing the inherent challenges of bridging these paradigms.