This podcast episode explores the impact of precision microbiome editing on climate change and human health. By modifying microbiomes with high precision, we can reduce methane emissions from sources like livestock, contributing to a more sustainable future. Precision microbiome editing also shows promise in addressing health issues such as asthma, obesity, diabetes, and Alzheimer's by targeting the gut microbiome. The collaboration between CRISPR and nature allows us to utilize the potential of tiny organisms to solve significant problems. This emerging field of precision microbiome editing has the potential to create a more resilient future for the planet and improve human health.