This podcast episode discusses the limitations of the energy balance model for weight management and introduces the carbohydrate insulin model as an alternative. It explores the impact of food on hormones, immune function, brain chemistry, gene expression, and the microbiome. The episode highlights the importance of considering individual factors and the complexity of energy regulation in the body. The carbohydrate insulin model emphasizes the quality of calories consumed, particularly refined carbs and sugars, and their impact on insulin levels and weight gain. The episode also addresses the role of toxins, genetics, hormones, and other factors in weight gain. It concludes by emphasizing the need to assess biomarkers, optimize metabolism, and reduce exposure to toxins for effective weight management.