This podcast episode discusses the diagnosis of spinal malformations and dysraphism, which includes a wide range of congenital abnormalities of the spine and spinal cord. Early detection and diagnosis are crucial for better patient outcomes and treatment decisions. The embryologic development of the spinal cord involves gastrulation, primary neurulation, and secondary neurulation, and abnormalities in these processes can lead to malformations. MRI is the preferred imaging modality for characterizing spinal malformations, while ultrasound plays a role in prenatal and neonatal screening. The episode covers various types of spinal dysraphism, including myelomeningocele seals and closed spinal dysraphism such as lipomas and meningisal. The diagnostic methods, locations, and associated neurological deficits are discussed. The podcast provides a comprehensive overview of spinal malformations encountered in clinical practice.