This podcast episode delves into the incredible journey of Sonia Vallabh, a biomedical researcher who discovered she had inherited the mutation for prion disease and dedicated her life to finding a treatment. It explores the life-changing experience of receiving a predictive genetic test report and the urgency to know one's genetic status. The episode also emphasizes the fatal nature of genetic prion disease and the mission to find a treatment. The speakers discuss the PRP protein's ability to go rogue and corrupt other copies in the brain, highlighting the need for innovative approaches to disease prevention. They assert the need for audacity in preventing and treating brain diseases and reflect on living with jeopardy. The episode concludes with an interview with Sonia Vallabh, who discusses the potential of treating monogenic diseases and its broader implications.
