Sebastian Kalamajski on genetic aspects of adiposity-related traits; Yuval Dor on DNA methylation–based assessment of pancreas and islet cells; and Carmella Evans-Molina on the role of calcium in regulating insulin secretion.

This podcast episode explores the research program on diabetes and adiposity-related traits, focusing on topics such as human genetic variation, DNA methylation patterns in the pancreas, and the role of alpha and beta cells in type 1 diabetes. The episode also features interviews with Dr. Carmella Evans-Molina and Dr. Sebastian Kalamajski, highlighting their research and personal experiences in the field. The discussions shed light on the challenges, controversies, and potential breakthroughs in diabetes research, emphasizing the importance of understanding cellular identity and exploring new tools for assessment and normalization.