Vance Spencer returns to Bankless to refresh his takes from his last appearance, 'The Bull Case For DeFi.' His predictions have held up exceptionally well, and listen in as he takes us through what Layer 2 means for the DeFi space.

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Bankless Podcast #68 - DeFi Verticals
Guest: Vance Spencer

Framework's Vance Spencer returns to Bankless nine months after his first appearance, 'The Bull Case for DeFi.' A lot has happened in the space since then, but his perspective holds up as salient and sharp. He and investing partner Michael Anderson have built a venture fund that invests in people.

With a healthy mix of on-chain and venture investments, Framework has consistently led as a thesis-driven firm with a clear focus on DeFi. Primitives, aggregators, and apps comprise a diverse and thoughtful portfolio representing a successful past and bullish future. It is increasingly apparent that capital efficiency is the game that DeFi projects are playing to gobble up market share.

Vance brings a uniquely holistic approach to investing in the space, discussing the verticalization of DeFi and seeking projects that leverage the smart contract money legoes to optimize front ends. The space's growth depends on building out payment rails, optimizing MEV, and exploring the world of rollups as a massive upgrade to the DeFi Sandbox. Stay tuned for hot predictions towards the end – this is somebody to listen to.

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Topics Covered:

0:00 Intro
6:00 Vance Spencer of Framework
9:15 Accelerating Innovation & TVL
12:25 Bullish Bear Market
15:00 Optimism, ETH, and BTC
20:11 Long-term Market Cycles
24:23 Speculation, Value, and Resilience
29:06 Narratives and Volatility
35:41 The DeFi Sandbox Today
42:14 What to Build Next
47:30 Institutional Aave
51:40 Enterprise Blockchain
56:03 Regulation
59:54 DeFi Layer 2 Summer
1:09:57 Derivatives & Games
1:13:30 Layer 2 Implications
1:19:40 Multi-Chain DeFi
1:23:44 Ultra-Sound Values
1:28:29 Eating the World
1:31:40 Information and DAOs
1:37:02 Be About That Life
1:42:00 Predictions
1:48:18 Framework Ventures
1:50:54 Closing & Disclaimers

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Resources:

Vance on Twitter:
https://twitter.com/pythianism?s=20

The Bull Case for DeFi:
https://newsletter.banklesshq.com/p/the-bull-case-for-defi-vance-spencer

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Not financial or tax advice. This channel is strictly educational and is not investment advice or a solicitation to buy or sell any assets or to make any financial decisions. This video is not tax advice. Talk to your accountant. Do your own research.

Disclosure. From time-to-time I may add links in this newsletter to products I use. I may receive commission if you make a purchase through one of these links. Additionally, the Bankless writers hold crypto assets. See our investment disclosures here:
https://newsletter.banklesshq.com/p/bankless-disclosures

68 - Bull Case for DeFi II | Vance Spencer

Bankless