This podcast episode delves into the evolution and future of JavaScript runtime environments, focusing on the creator of Node.js and Deno, Ryan Dahl. The discussion highlights the growth of Node.js and its hindrances due to widespread adoption. It introduces Deno as a modern distribution of V8, emphasizing its simplicity, robustness, and compatibility with the JavaScript ecosystem. The conversation also covers the development of Deno, the benefits of using JSR (JavaScript Registry) for package distribution, the challenges of HTTP URLs as a module system, and the significance of ESM (ECMAScript Modules). Additionally, topics such as Deno Deploy, state management, Deno Subhosting, executing untrusted code, and the future of JavaScript runtimes are explored.