This podcast episode delves into the fascinating journey of rapamycin from its origins in the soil of Easter Island to its FDA approval and potential applications in extending lifespan and healthspan, with insights from experts Peter Attia, David Sabatini, and Navdeep Chandel. They discuss the intricate relationship between rapamycin and mTOR, the importance of balancing lifespan with healthspan, and the need for scientific rigor in aging research, all underscored by personal experiences and anecdotes that highlight the challenges and promises of longevity interventions.