According to recent data, roughly ten percent of pregnant women take an antidepressant. Numerous research studies have shown that antidepressants cross the placenta. What effect does this chemical exposure have on the developing fetus?

Dr. Adam Urato is a Maternal-Fetal Medicine (MFM) physician in Framingham, Massachusetts. He is an expert witness in antidepressant litigation and writes and lectures regularly on antidepressant use during pregnancy. Dr. Urato attended Harvard College and Harvard Medical School, and completed his OB/GYN residency at Massachusetts General Hospital and Brigham and Women's Hospital. He completed his Maternal-Fetal Medicine Fellowship at Tufts Medical Center. Dr. Urato has an active clinical practice taking care of high-risk pregnancies and delivering babies.

Adam Urato, MD (@AdamUrato1) / X

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This discussion is about warning and the public's need to be aware of what the science is showing about the use of antidepressants in pregnancy.

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ADDITIONAL RESOURCES

9:00 - Maternal serotonin is crucial for murine embryonic development | PNAS

10:30 - New Insights into How Serotonin Selective Reuptake Inhibitors Shape the Developing Brain - PMC

12:00 - Antidepressant Prescription Claims Among Reproductive-Aged Women With Private Employer-Sponsored Insurance — United States 2008–2013 | MMWR

13:00 - Rate of Chiari I Malformation in Children of Mothers with Depression with and without Prenatal SSRI Exposure

13:30 - Prenatal exposure to antidepressants and persistent pulmonary hypertension of the newborn: systematic review and meta-analysis | The BMJ

14:30 - Modulation of serotonin transporter function during fetal development causes dilated heart cardiomyopathy and lifelong behavioral abnormalities

15:30 - Exposure to selective serotonin reuptake inhibitors during pregnancy and risk of autism spectrum disorder in children: a systematic review and meta-analysis of observational studies

16:30 - April 17, 2023 Tweet: Dr. Urato MRI's studies of SSRI exposed prenatal babies developing brains

17:30 - Neonatal withdrawal syndrome following in utero exposure to antidepressants: a disproportionality analysis of VigiBase, the WHO spontaneous reporting database

30:00 - Comparison of the effect of sertraline with behavioral therapy on semen parameters in men with primary premature ejaculation

40:00 - How to survive the medical misinformation mess - Ioannidis - 2017 - European Journal of Clinical Investigation - Wiley Online Library

42:30 - Multigenerational adversity impacts on human gut microbiome composition and socioemotional functioning in early childhood | PNAS

44:00 - Prenatal Antidepressant Exposures and Gastrointestinal Complaints in Childhood: A Gut-Brain Axis Connection? - PMC

47:00 - Stanford Research into the Impact of Tobacco Advertising: T-Zone

48:30 - The DES story: long-term consequences of prenatal exposure

100. Antidepressants During Pregnancy and Postpartum: What You Need to Know w/ Dr. Adam Urato

Radically Genuine Podcast with Dr. Roger McFillin