This podcast episode explores the decline in the number of postdocs in academia and the increasing number of young life scientists leaving academia for industry. It discusses the reasons behind these trends, including the increasing cost of living, difficulty finding faculty positions, and the availability of high-paying jobs in industry. The podcast also examines the financial and demographic factors influencing the decision to pursue a postdoc and the impact of the exodus of researchers on academic research. The episode highlights the tipping point in academia, leading to irreversible changes in the research landscape, and the efforts of organizations like the NIH to address issues within the postdoc system. The speakers discuss the impact of industry jobs on the scientific career pipeline and the challenges faced by postdocs in academia. They also raise concerns about the current academic training model and suggest alternative approaches. Ultimately, the episode emphasizes the need to ensure diversity and a welcoming environment in academia and the importance of representation in science.