This podcast episode explores the connection between the Sackler family and the opioid crisis, as discussed in Patrick Radden Keefe's book, "Empire of Pain." The Sacklers, known for their involvement with Purdue Pharma and the creation of Oxycontin, have become synonymous with the controversial practices of the company. The sections delve into the marketing tactics employed by Purdue, the Sacklers' denial of wrongdoing, and the impact of their actions on the opioid crisis. Despite the immense harm caused, the Sacklers have never admitted their involvement or taken responsibility.